il22 egfp reporter mice 43 Search Results


niaid taconic contract line 103 il22  (Taconic Biosciences)
93
Taconic Biosciences niaid taconic contract line 103 il22
Niaid Taconic Contract Line 103 Il22, supplied by Taconic Biosciences, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/il22+egfp+reporter+mice+43/Il22/pm33385336-200-50-51
Average 93 stars, based on 1 article reviews
niaid taconic contract line 103 il22 - by Bioz Stars, 2026-11
93/100 stars
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b6 f b6 m c57bl 10 mice niaid taconic contract line 8411 oligonucleotides cauf 5  (Taconic Biosciences)
95
Taconic Biosciences b6 f b6 m c57bl 10 mice niaid taconic contract line 8411 oligonucleotides cauf 5
B6 F B6 M C57bl 10 Mice Niaid Taconic Contract Line 8411 Oligonucleotides Cauf 5, supplied by Taconic Biosciences, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/il22+egfp+reporter+mice+43/Black+6/pm33385336-200-83-87
Average 95 stars, based on 1 article reviews
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lsrfortessa  (Becton Dickinson)
90
Becton Dickinson lsrfortessa
Lsrfortessa, supplied by Becton Dickinson, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/il22+egfp+reporter+mice+43/facscalibur+flow+cytometer/pm33385336-200-138-139
Average 90 stars, based on 1 article reviews
lsrfortessa - by Bioz Stars, 2026-11
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il2rg  (Taconic Biosciences)
97
Taconic Biosciences il2rg
Figure 3. Immunodeficient <t>Rag2–/–</t> and <t>Rag2–/–Il2rg–/–</t> mice exhibit a greater propensity for C. auris skin colonization (A) IL-17A and IL-17F production by ILCs is increased in the skin of Rag2/ mice. Shown are numbers of IL-17A-producing (left panel) and IL-17F-producing (right panel) ILCs in the skin of WT and Rag2-deficient mice at steady state and 7 days after C. auris colonization. The statistics were calculated using the t test or Mann-Whitney U test, as appropriate. n = 6–9 mice for each group; two independent experiments. Data are mean ± SEM. (B) Rag2/ mice are defective in controlling C. auris colonization on the ear skin surface (CFU/swab) and within the tissue compartment (CFU/gram of tissue). The statistics were calculated using the t test or Mann-Whitney U test, as appropriate. n = 9–10 mice for each group; two independent experiments. (C) Immunodeficient Rag2/Il2rg/ mice are defective in clearing C. auris from the ear and back skin surface (CFU/swab) and tissue (CFU/gram of tissue); and intestinal compartments (CFU/gram of intestinal content) as determined by culturing from WT and Rag2/Il2rg/ mice 2 weeks after topical colonization. The statistics were calculated using the Mann-Whitney U test. n = 5 mice for each group, representative of two independent experiments. Data are shown with mean ± SEM. See also Figures S4G and S4H. (D) Longitudinally, WT and Rag2/Il2rg/ mouse skin swabs were cultured for C. auris on days 4, 10, 17, 24, and 32, and extended through days 59, 91, and 119 for Rag2/Il2rg/ mice. The Mann-Whitney U test was used to compare between WT and Rag2/Il2rg/ mice at each time point up to day 32. n = 6 mice for each group, representative of three independent experiments. Data are shown with mean ± SEM. (E) Immunodeficient Rag2/Il2rg/ mice are defective in clearing C. auris from the ear and back skin tissues (CFU/gram of tissue); and intestinal compartments (CFU/gram of intestinal content) as measured by culturing from WT and Rag2/Il2rg/ mice 208 days after topical association. No C. auris colonies were cultured from WT mice on day 208. n = 6 mice for each group, representative of three independent experiments. Data are shown with mean ± SEM. ND, not detected.
Il2rg, supplied by Taconic Biosciences, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/il22+egfp+reporter+mice+43/Rag2+-+Model+RAG2/pm33385336-200-43-40
Average 97 stars, based on 1 article reviews
il2rg - by Bioz Stars, 2026-11
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ultra-sensitive mouse insulin elisa kit  (Crystal Chem Inc)
90
Crystal Chem Inc ultra-sensitive mouse insulin elisa kit
Figure 3. Immunodeficient <t>Rag2–/–</t> and <t>Rag2–/–Il2rg–/–</t> mice exhibit a greater propensity for C. auris skin colonization (A) IL-17A and IL-17F production by ILCs is increased in the skin of Rag2/ mice. Shown are numbers of IL-17A-producing (left panel) and IL-17F-producing (right panel) ILCs in the skin of WT and Rag2-deficient mice at steady state and 7 days after C. auris colonization. The statistics were calculated using the t test or Mann-Whitney U test, as appropriate. n = 6–9 mice for each group; two independent experiments. Data are mean ± SEM. (B) Rag2/ mice are defective in controlling C. auris colonization on the ear skin surface (CFU/swab) and within the tissue compartment (CFU/gram of tissue). The statistics were calculated using the t test or Mann-Whitney U test, as appropriate. n = 9–10 mice for each group; two independent experiments. (C) Immunodeficient Rag2/Il2rg/ mice are defective in clearing C. auris from the ear and back skin surface (CFU/swab) and tissue (CFU/gram of tissue); and intestinal compartments (CFU/gram of intestinal content) as determined by culturing from WT and Rag2/Il2rg/ mice 2 weeks after topical colonization. The statistics were calculated using the Mann-Whitney U test. n = 5 mice for each group, representative of two independent experiments. Data are shown with mean ± SEM. See also Figures S4G and S4H. (D) Longitudinally, WT and Rag2/Il2rg/ mouse skin swabs were cultured for C. auris on days 4, 10, 17, 24, and 32, and extended through days 59, 91, and 119 for Rag2/Il2rg/ mice. The Mann-Whitney U test was used to compare between WT and Rag2/Il2rg/ mice at each time point up to day 32. n = 6 mice for each group, representative of three independent experiments. Data are shown with mean ± SEM. (E) Immunodeficient Rag2/Il2rg/ mice are defective in clearing C. auris from the ear and back skin tissues (CFU/gram of tissue); and intestinal compartments (CFU/gram of intestinal content) as measured by culturing from WT and Rag2/Il2rg/ mice 208 days after topical association. No C. auris colonies were cultured from WT mice on day 208. n = 6 mice for each group, representative of three independent experiments. Data are shown with mean ± SEM. ND, not detected.
Ultra Sensitive Mouse Insulin Elisa Kit, supplied by Crystal Chem Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/il22+egfp+reporter+mice+43/ultra+sensitive+mouse+insulin+elisa+kit/pm39675006-220-206-212
Average 90 stars, based on 1 article reviews
ultra-sensitive mouse insulin elisa kit - by Bioz Stars, 2026-11
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recombinant proteins mouse tnf  (Novoprotein)
86
Novoprotein recombinant proteins mouse tnf
Figure 3. Immunodeficient <t>Rag2–/–</t> and <t>Rag2–/–Il2rg–/–</t> mice exhibit a greater propensity for C. auris skin colonization (A) IL-17A and IL-17F production by ILCs is increased in the skin of Rag2/ mice. Shown are numbers of IL-17A-producing (left panel) and IL-17F-producing (right panel) ILCs in the skin of WT and Rag2-deficient mice at steady state and 7 days after C. auris colonization. The statistics were calculated using the t test or Mann-Whitney U test, as appropriate. n = 6–9 mice for each group; two independent experiments. Data are mean ± SEM. (B) Rag2/ mice are defective in controlling C. auris colonization on the ear skin surface (CFU/swab) and within the tissue compartment (CFU/gram of tissue). The statistics were calculated using the t test or Mann-Whitney U test, as appropriate. n = 9–10 mice for each group; two independent experiments. (C) Immunodeficient Rag2/Il2rg/ mice are defective in clearing C. auris from the ear and back skin surface (CFU/swab) and tissue (CFU/gram of tissue); and intestinal compartments (CFU/gram of intestinal content) as determined by culturing from WT and Rag2/Il2rg/ mice 2 weeks after topical colonization. The statistics were calculated using the Mann-Whitney U test. n = 5 mice for each group, representative of two independent experiments. Data are shown with mean ± SEM. See also Figures S4G and S4H. (D) Longitudinally, WT and Rag2/Il2rg/ mouse skin swabs were cultured for C. auris on days 4, 10, 17, 24, and 32, and extended through days 59, 91, and 119 for Rag2/Il2rg/ mice. The Mann-Whitney U test was used to compare between WT and Rag2/Il2rg/ mice at each time point up to day 32. n = 6 mice for each group, representative of three independent experiments. Data are shown with mean ± SEM. (E) Immunodeficient Rag2/Il2rg/ mice are defective in clearing C. auris from the ear and back skin tissues (CFU/gram of tissue); and intestinal compartments (CFU/gram of intestinal content) as measured by culturing from WT and Rag2/Il2rg/ mice 208 days after topical association. No C. auris colonies were cultured from WT mice on day 208. n = 6 mice for each group, representative of three independent experiments. Data are shown with mean ± SEM. ND, not detected.
Recombinant Proteins Mouse Tnf, supplied by Novoprotein, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/il22+egfp+reporter+mice+43/human+recombinant+tnf+%CE%B1/pm39325617-237-64-74
Average 86 stars, based on 1 article reviews
recombinant proteins mouse tnf - by Bioz Stars, 2026-11
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mouse ctn 1 elisa kit  (Cusabio)
93
Cusabio mouse ctn 1 elisa kit
Figure 3. Immunodeficient <t>Rag2–/–</t> and <t>Rag2–/–Il2rg–/–</t> mice exhibit a greater propensity for C. auris skin colonization (A) IL-17A and IL-17F production by ILCs is increased in the skin of Rag2/ mice. Shown are numbers of IL-17A-producing (left panel) and IL-17F-producing (right panel) ILCs in the skin of WT and Rag2-deficient mice at steady state and 7 days after C. auris colonization. The statistics were calculated using the t test or Mann-Whitney U test, as appropriate. n = 6–9 mice for each group; two independent experiments. Data are mean ± SEM. (B) Rag2/ mice are defective in controlling C. auris colonization on the ear skin surface (CFU/swab) and within the tissue compartment (CFU/gram of tissue). The statistics were calculated using the t test or Mann-Whitney U test, as appropriate. n = 9–10 mice for each group; two independent experiments. (C) Immunodeficient Rag2/Il2rg/ mice are defective in clearing C. auris from the ear and back skin surface (CFU/swab) and tissue (CFU/gram of tissue); and intestinal compartments (CFU/gram of intestinal content) as determined by culturing from WT and Rag2/Il2rg/ mice 2 weeks after topical colonization. The statistics were calculated using the Mann-Whitney U test. n = 5 mice for each group, representative of two independent experiments. Data are shown with mean ± SEM. See also Figures S4G and S4H. (D) Longitudinally, WT and Rag2/Il2rg/ mouse skin swabs were cultured for C. auris on days 4, 10, 17, 24, and 32, and extended through days 59, 91, and 119 for Rag2/Il2rg/ mice. The Mann-Whitney U test was used to compare between WT and Rag2/Il2rg/ mice at each time point up to day 32. n = 6 mice for each group, representative of three independent experiments. Data are shown with mean ± SEM. (E) Immunodeficient Rag2/Il2rg/ mice are defective in clearing C. auris from the ear and back skin tissues (CFU/gram of tissue); and intestinal compartments (CFU/gram of intestinal content) as measured by culturing from WT and Rag2/Il2rg/ mice 208 days after topical association. No C. auris colonies were cultured from WT mice on day 208. n = 6 mice for each group, representative of three independent experiments. Data are shown with mean ± SEM. ND, not detected.
Mouse Ctn 1 Elisa Kit, supplied by Cusabio, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/il22+egfp+reporter+mice+43/Mouse+cardiac+troponin+%E2%85%A0(cTn-%E2%85%A0)+ELISA+kit/pm39325617-237-152-156
Average 93 stars, based on 1 article reviews
mouse ctn 1 elisa kit - by Bioz Stars, 2026-11
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be0075 1 invivomab anti mouse gm csf bioxcell  (Bio X Cell)
94
Bio X Cell be0075 1 invivomab anti mouse gm csf bioxcell
Figure 3. Immunodeficient <t>Rag2–/–</t> and <t>Rag2–/–Il2rg–/–</t> mice exhibit a greater propensity for C. auris skin colonization (A) IL-17A and IL-17F production by ILCs is increased in the skin of Rag2/ mice. Shown are numbers of IL-17A-producing (left panel) and IL-17F-producing (right panel) ILCs in the skin of WT and Rag2-deficient mice at steady state and 7 days after C. auris colonization. The statistics were calculated using the t test or Mann-Whitney U test, as appropriate. n = 6–9 mice for each group; two independent experiments. Data are mean ± SEM. (B) Rag2/ mice are defective in controlling C. auris colonization on the ear skin surface (CFU/swab) and within the tissue compartment (CFU/gram of tissue). The statistics were calculated using the t test or Mann-Whitney U test, as appropriate. n = 9–10 mice for each group; two independent experiments. (C) Immunodeficient Rag2/Il2rg/ mice are defective in clearing C. auris from the ear and back skin surface (CFU/swab) and tissue (CFU/gram of tissue); and intestinal compartments (CFU/gram of intestinal content) as determined by culturing from WT and Rag2/Il2rg/ mice 2 weeks after topical colonization. The statistics were calculated using the Mann-Whitney U test. n = 5 mice for each group, representative of two independent experiments. Data are shown with mean ± SEM. See also Figures S4G and S4H. (D) Longitudinally, WT and Rag2/Il2rg/ mouse skin swabs were cultured for C. auris on days 4, 10, 17, 24, and 32, and extended through days 59, 91, and 119 for Rag2/Il2rg/ mice. The Mann-Whitney U test was used to compare between WT and Rag2/Il2rg/ mice at each time point up to day 32. n = 6 mice for each group, representative of three independent experiments. Data are shown with mean ± SEM. (E) Immunodeficient Rag2/Il2rg/ mice are defective in clearing C. auris from the ear and back skin tissues (CFU/gram of tissue); and intestinal compartments (CFU/gram of intestinal content) as measured by culturing from WT and Rag2/Il2rg/ mice 208 days after topical association. No C. auris colonies were cultured from WT mice on day 208. n = 6 mice for each group, representative of three independent experiments. Data are shown with mean ± SEM. ND, not detected.
Be0075 1 Invivomab Anti Mouse Gm Csf Bioxcell, supplied by Bio X Cell, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 94 stars, based on 1 article reviews
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mouse il 6 elisa kit ebioscence  (Proteintech)
96
Proteintech mouse il 6 elisa kit ebioscence
Figure 3. Immunodeficient <t>Rag2–/–</t> and <t>Rag2–/–Il2rg–/–</t> mice exhibit a greater propensity for C. auris skin colonization (A) IL-17A and IL-17F production by ILCs is increased in the skin of Rag2/ mice. Shown are numbers of IL-17A-producing (left panel) and IL-17F-producing (right panel) ILCs in the skin of WT and Rag2-deficient mice at steady state and 7 days after C. auris colonization. The statistics were calculated using the t test or Mann-Whitney U test, as appropriate. n = 6–9 mice for each group; two independent experiments. Data are mean ± SEM. (B) Rag2/ mice are defective in controlling C. auris colonization on the ear skin surface (CFU/swab) and within the tissue compartment (CFU/gram of tissue). The statistics were calculated using the t test or Mann-Whitney U test, as appropriate. n = 9–10 mice for each group; two independent experiments. (C) Immunodeficient Rag2/Il2rg/ mice are defective in clearing C. auris from the ear and back skin surface (CFU/swab) and tissue (CFU/gram of tissue); and intestinal compartments (CFU/gram of intestinal content) as determined by culturing from WT and Rag2/Il2rg/ mice 2 weeks after topical colonization. The statistics were calculated using the Mann-Whitney U test. n = 5 mice for each group, representative of two independent experiments. Data are shown with mean ± SEM. See also Figures S4G and S4H. (D) Longitudinally, WT and Rag2/Il2rg/ mouse skin swabs were cultured for C. auris on days 4, 10, 17, 24, and 32, and extended through days 59, 91, and 119 for Rag2/Il2rg/ mice. The Mann-Whitney U test was used to compare between WT and Rag2/Il2rg/ mice at each time point up to day 32. n = 6 mice for each group, representative of three independent experiments. Data are shown with mean ± SEM. (E) Immunodeficient Rag2/Il2rg/ mice are defective in clearing C. auris from the ear and back skin tissues (CFU/gram of tissue); and intestinal compartments (CFU/gram of intestinal content) as measured by culturing from WT and Rag2/Il2rg/ mice 208 days after topical association. No C. auris colonies were cultured from WT mice on day 208. n = 6 mice for each group, representative of three independent experiments. Data are shown with mean ± SEM. ND, not detected.
Mouse Il 6 Elisa Kit Ebioscence, supplied by Proteintech, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/il22+egfp+reporter+mice+43/Mouse+IL-6+ELISA+Kit/pm39325617-237-110-121
Average 96 stars, based on 1 article reviews
mouse il 6 elisa kit ebioscence - by Bioz Stars, 2026-11
96/100 stars
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mouse il 1b elisa kit proteintech  (Proteintech)
96
Proteintech mouse il 1b elisa kit proteintech
Figure 3. Immunodeficient <t>Rag2–/–</t> and <t>Rag2–/–Il2rg–/–</t> mice exhibit a greater propensity for C. auris skin colonization (A) IL-17A and IL-17F production by ILCs is increased in the skin of Rag2/ mice. Shown are numbers of IL-17A-producing (left panel) and IL-17F-producing (right panel) ILCs in the skin of WT and Rag2-deficient mice at steady state and 7 days after C. auris colonization. The statistics were calculated using the t test or Mann-Whitney U test, as appropriate. n = 6–9 mice for each group; two independent experiments. Data are mean ± SEM. (B) Rag2/ mice are defective in controlling C. auris colonization on the ear skin surface (CFU/swab) and within the tissue compartment (CFU/gram of tissue). The statistics were calculated using the t test or Mann-Whitney U test, as appropriate. n = 9–10 mice for each group; two independent experiments. (C) Immunodeficient Rag2/Il2rg/ mice are defective in clearing C. auris from the ear and back skin surface (CFU/swab) and tissue (CFU/gram of tissue); and intestinal compartments (CFU/gram of intestinal content) as determined by culturing from WT and Rag2/Il2rg/ mice 2 weeks after topical colonization. The statistics were calculated using the Mann-Whitney U test. n = 5 mice for each group, representative of two independent experiments. Data are shown with mean ± SEM. See also Figures S4G and S4H. (D) Longitudinally, WT and Rag2/Il2rg/ mouse skin swabs were cultured for C. auris on days 4, 10, 17, 24, and 32, and extended through days 59, 91, and 119 for Rag2/Il2rg/ mice. The Mann-Whitney U test was used to compare between WT and Rag2/Il2rg/ mice at each time point up to day 32. n = 6 mice for each group, representative of three independent experiments. Data are shown with mean ± SEM. (E) Immunodeficient Rag2/Il2rg/ mice are defective in clearing C. auris from the ear and back skin tissues (CFU/gram of tissue); and intestinal compartments (CFU/gram of intestinal content) as measured by culturing from WT and Rag2/Il2rg/ mice 208 days after topical association. No C. auris colonies were cultured from WT mice on day 208. n = 6 mice for each group, representative of three independent experiments. Data are shown with mean ± SEM. ND, not detected.
Mouse Il 1b Elisa Kit Proteintech, supplied by Proteintech, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/il22+egfp+reporter+mice+43/Mouse+IL-1+beta+ELISA+Kit/pm39325617-237-117-121
Average 96 stars, based on 1 article reviews
mouse il 1b elisa kit proteintech - by Bioz Stars, 2026-11
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invivomab anti mouse ly6g bioxcell  (Bio X Cell)
96
Bio X Cell invivomab anti mouse ly6g bioxcell
Figure 3. Immunodeficient <t>Rag2–/–</t> and <t>Rag2–/–Il2rg–/–</t> mice exhibit a greater propensity for C. auris skin colonization (A) IL-17A and IL-17F production by ILCs is increased in the skin of Rag2/ mice. Shown are numbers of IL-17A-producing (left panel) and IL-17F-producing (right panel) ILCs in the skin of WT and Rag2-deficient mice at steady state and 7 days after C. auris colonization. The statistics were calculated using the t test or Mann-Whitney U test, as appropriate. n = 6–9 mice for each group; two independent experiments. Data are mean ± SEM. (B) Rag2/ mice are defective in controlling C. auris colonization on the ear skin surface (CFU/swab) and within the tissue compartment (CFU/gram of tissue). The statistics were calculated using the t test or Mann-Whitney U test, as appropriate. n = 9–10 mice for each group; two independent experiments. (C) Immunodeficient Rag2/Il2rg/ mice are defective in clearing C. auris from the ear and back skin surface (CFU/swab) and tissue (CFU/gram of tissue); and intestinal compartments (CFU/gram of intestinal content) as determined by culturing from WT and Rag2/Il2rg/ mice 2 weeks after topical colonization. The statistics were calculated using the Mann-Whitney U test. n = 5 mice for each group, representative of two independent experiments. Data are shown with mean ± SEM. See also Figures S4G and S4H. (D) Longitudinally, WT and Rag2/Il2rg/ mouse skin swabs were cultured for C. auris on days 4, 10, 17, 24, and 32, and extended through days 59, 91, and 119 for Rag2/Il2rg/ mice. The Mann-Whitney U test was used to compare between WT and Rag2/Il2rg/ mice at each time point up to day 32. n = 6 mice for each group, representative of three independent experiments. Data are shown with mean ± SEM. (E) Immunodeficient Rag2/Il2rg/ mice are defective in clearing C. auris from the ear and back skin tissues (CFU/gram of tissue); and intestinal compartments (CFU/gram of intestinal content) as measured by culturing from WT and Rag2/Il2rg/ mice 208 days after topical association. No C. auris colonies were cultured from WT mice on day 208. n = 6 mice for each group, representative of three independent experiments. Data are shown with mean ± SEM. ND, not detected.
Invivomab Anti Mouse Ly6g Bioxcell, supplied by Bio X Cell, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 96 stars, based on 1 article reviews
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c3h/hej  (Jackson Laboratory)
90
Jackson Laboratory c3h/hej
Figure 3. Immunodeficient <t>Rag2–/–</t> and <t>Rag2–/–Il2rg–/–</t> mice exhibit a greater propensity for C. auris skin colonization (A) IL-17A and IL-17F production by ILCs is increased in the skin of Rag2/ mice. Shown are numbers of IL-17A-producing (left panel) and IL-17F-producing (right panel) ILCs in the skin of WT and Rag2-deficient mice at steady state and 7 days after C. auris colonization. The statistics were calculated using the t test or Mann-Whitney U test, as appropriate. n = 6–9 mice for each group; two independent experiments. Data are mean ± SEM. (B) Rag2/ mice are defective in controlling C. auris colonization on the ear skin surface (CFU/swab) and within the tissue compartment (CFU/gram of tissue). The statistics were calculated using the t test or Mann-Whitney U test, as appropriate. n = 9–10 mice for each group; two independent experiments. (C) Immunodeficient Rag2/Il2rg/ mice are defective in clearing C. auris from the ear and back skin surface (CFU/swab) and tissue (CFU/gram of tissue); and intestinal compartments (CFU/gram of intestinal content) as determined by culturing from WT and Rag2/Il2rg/ mice 2 weeks after topical colonization. The statistics were calculated using the Mann-Whitney U test. n = 5 mice for each group, representative of two independent experiments. Data are shown with mean ± SEM. See also Figures S4G and S4H. (D) Longitudinally, WT and Rag2/Il2rg/ mouse skin swabs were cultured for C. auris on days 4, 10, 17, 24, and 32, and extended through days 59, 91, and 119 for Rag2/Il2rg/ mice. The Mann-Whitney U test was used to compare between WT and Rag2/Il2rg/ mice at each time point up to day 32. n = 6 mice for each group, representative of three independent experiments. Data are shown with mean ± SEM. (E) Immunodeficient Rag2/Il2rg/ mice are defective in clearing C. auris from the ear and back skin tissues (CFU/gram of tissue); and intestinal compartments (CFU/gram of intestinal content) as measured by culturing from WT and Rag2/Il2rg/ mice 208 days after topical association. No C. auris colonies were cultured from WT mice on day 208. n = 6 mice for each group, representative of three independent experiments. Data are shown with mean ± SEM. ND, not detected.
C3h/Hej, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/il22+egfp+reporter+mice+43/c3heb+fej+mice/pm38457343-153-155-158
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c3h/hej - by Bioz Stars, 2026-11
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Image Search Results


Figure 3. Immunodeficient Rag2–/– and Rag2–/–Il2rg–/– mice exhibit a greater propensity for C. auris skin colonization (A) IL-17A and IL-17F production by ILCs is increased in the skin of Rag2/ mice. Shown are numbers of IL-17A-producing (left panel) and IL-17F-producing (right panel) ILCs in the skin of WT and Rag2-deficient mice at steady state and 7 days after C. auris colonization. The statistics were calculated using the t test or Mann-Whitney U test, as appropriate. n = 6–9 mice for each group; two independent experiments. Data are mean ± SEM. (B) Rag2/ mice are defective in controlling C. auris colonization on the ear skin surface (CFU/swab) and within the tissue compartment (CFU/gram of tissue). The statistics were calculated using the t test or Mann-Whitney U test, as appropriate. n = 9–10 mice for each group; two independent experiments. (C) Immunodeficient Rag2/Il2rg/ mice are defective in clearing C. auris from the ear and back skin surface (CFU/swab) and tissue (CFU/gram of tissue); and intestinal compartments (CFU/gram of intestinal content) as determined by culturing from WT and Rag2/Il2rg/ mice 2 weeks after topical colonization. The statistics were calculated using the Mann-Whitney U test. n = 5 mice for each group, representative of two independent experiments. Data are shown with mean ± SEM. See also Figures S4G and S4H. (D) Longitudinally, WT and Rag2/Il2rg/ mouse skin swabs were cultured for C. auris on days 4, 10, 17, 24, and 32, and extended through days 59, 91, and 119 for Rag2/Il2rg/ mice. The Mann-Whitney U test was used to compare between WT and Rag2/Il2rg/ mice at each time point up to day 32. n = 6 mice for each group, representative of three independent experiments. Data are shown with mean ± SEM. (E) Immunodeficient Rag2/Il2rg/ mice are defective in clearing C. auris from the ear and back skin tissues (CFU/gram of tissue); and intestinal compartments (CFU/gram of intestinal content) as measured by culturing from WT and Rag2/Il2rg/ mice 208 days after topical association. No C. auris colonies were cultured from WT mice on day 208. n = 6 mice for each group, representative of three independent experiments. Data are shown with mean ± SEM. ND, not detected.

Journal: Cell host & microbe

Article Title: Murine model of colonization with fungal pathogen Candida auris to explore skin tropism, host risk factors and therapeutic strategies.

doi: 10.1016/j.chom.2020.12.002

Figure Lengend Snippet: Figure 3. Immunodeficient Rag2–/– and Rag2–/–Il2rg–/– mice exhibit a greater propensity for C. auris skin colonization (A) IL-17A and IL-17F production by ILCs is increased in the skin of Rag2/ mice. Shown are numbers of IL-17A-producing (left panel) and IL-17F-producing (right panel) ILCs in the skin of WT and Rag2-deficient mice at steady state and 7 days after C. auris colonization. The statistics were calculated using the t test or Mann-Whitney U test, as appropriate. n = 6–9 mice for each group; two independent experiments. Data are mean ± SEM. (B) Rag2/ mice are defective in controlling C. auris colonization on the ear skin surface (CFU/swab) and within the tissue compartment (CFU/gram of tissue). The statistics were calculated using the t test or Mann-Whitney U test, as appropriate. n = 9–10 mice for each group; two independent experiments. (C) Immunodeficient Rag2/Il2rg/ mice are defective in clearing C. auris from the ear and back skin surface (CFU/swab) and tissue (CFU/gram of tissue); and intestinal compartments (CFU/gram of intestinal content) as determined by culturing from WT and Rag2/Il2rg/ mice 2 weeks after topical colonization. The statistics were calculated using the Mann-Whitney U test. n = 5 mice for each group, representative of two independent experiments. Data are shown with mean ± SEM. See also Figures S4G and S4H. (D) Longitudinally, WT and Rag2/Il2rg/ mouse skin swabs were cultured for C. auris on days 4, 10, 17, 24, and 32, and extended through days 59, 91, and 119 for Rag2/Il2rg/ mice. The Mann-Whitney U test was used to compare between WT and Rag2/Il2rg/ mice at each time point up to day 32. n = 6 mice for each group, representative of three independent experiments. Data are shown with mean ± SEM. (E) Immunodeficient Rag2/Il2rg/ mice are defective in clearing C. auris from the ear and back skin tissues (CFU/gram of tissue); and intestinal compartments (CFU/gram of intestinal content) as measured by culturing from WT and Rag2/Il2rg/ mice 208 days after topical association. No C. auris colonies were cultured from WT mice on day 208. n = 6 mice for each group, representative of three independent experiments. Data are shown with mean ± SEM. ND, not detected.

Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER Yeast Extract-Peptone-Dextrose (YPD) Broth BD Bioscience Cat # 242820 eBioscience Fixation/Permeabilization Concentrate eBioscience Cat #00-5123-43 eBioscience Fixation/Permeabilization Diluent eBioscience Cat #00-5223-56 eBioscience Permeabilization Buffer (10X) eBioscience Cat #00-8333-56 Experimental Models: Organisms/Strains Diabetic mice (db/db) NIAID Taconic Contract N/A Rag2-/-Il2rg-/- NIAID Taconic Contract Line 111 Rag2-/- NIAID Taconic Contract Line 103 Il22-/- Dr. Yasmine Belkaid N/A Card9-/- Dr. Michail S. Lionakis N/A Act1-/- NIAID Taconic Contract Line 290 Lan-DTA Dr. Yasmine Belkaid N/A C57BL/6 mice Taconic Biosciences Cat # B6-F/B6-M C57BL/10 mice NIAID Taconic Contract Line 8411 Oligonucleotides CauF 5’-CGCACATTGCGCCTTGGGGTA-3’ Thermo Scientific N/A CauR 5’-GTAGTCCTACCTGATTTGAGGCGAC-3’ Thermo Scientific N/A Software and Algorithms FlowJo v9 Tree Star https://www.flowjo.com/solutions/ flowjo/downloads GraphPad Prism 4 GraphPad Software https://www.graphpad.com/ scientificsoftware/prism/ R v3.6.0 The R Foundation https://www.r-project.org/ Other Medimachine BD Bioscience Cat # 340588 MediMachine II Syntec International Cat # 121600 LSRFortessa BD Biosciences https://www.bd.com/en-us/offerings/ brands/lsrfortessa LSR II BD Biosciences https://www.bdbiosciences.com/ en-us/go-campaign/lsr-ii-comp-cont QuantStudio 6 Flex Fisher Scientific https://www.fishersci.com/shop/products/ 6-flx96wfast-instlptp-1-system/4485699 GMS staining of mouse ear skin sections Histoserv N/A

Techniques: MANN-WHITNEY, Cell Culture

Figure 4. Skin antiseptic chlorhexidine pro- tects WT mice from C. auris colonization and promotes C. auris decolonization of Rag2–/–Il2rg–/– mice (A) Schematic for experimental design to model CHG skin bathing. Wipes impregnated with CHG were used daily for 4 days to ‘‘bathe’’ the mouse skin before topical association. A cotton gauze saturated with sterile PBS was used as the proce- dural control. C. auris cells were topically associ- ated onto mouse ear pinna and dorsal back skin at two concentrations: 107 CFU as medium concen- tration, and 109 CFU as high concentration. After topical association, CHG was applied every other day for the duration of the experiment. Skin swabs were taken during the experiment and skin tissues were disaggregated at the end of the experiment and processed for C. auris culturing. (B) CHG bathing protects WT mouse skin from C. auris topical exposure (medium and high con- centrations) as measured by culturing skin swabs. n = 4 mice for each group, representative of two independent experiments. (C) CHG bathing protects WT mouse skin tissue from C. auris residence after topical exposure (me- dium and high concentrations). n = 4 mice for each group, representative of two independent experi- ments. (D) Schematic for experimental design to model CHG skin bathing to promote C. auris decoloniza- tion. After C. auris (medium and high concentra- tions) topical association, daily bathing with CHG was deployed for 1 week. Skin swabs were taken during the experiment and skin tissues were dis- aggregated at the end of the experiment for culturing. (E) CHG bathing promotes C. auris decolonization on Rag2/Il2rg/ ear skin swabs 4 and 10 days after high concentration topical exposure. The sta- tistics were calculated using the t test. n = 5 mice for each group, representative of two independent experiments. (F) CHG bathing promotes C. auris decolonization in Rag2/Il2rg/ resident skin tissue after medium and high concentration topical exposure. n = 5 mice for each group, representative of two independent experiments. See also Table S3. The statistics for (B), (C), (E), and (F) were calculated using the t test. *p < 0.05, **p < 0.01.

Journal: Cell host & microbe

Article Title: Murine model of colonization with fungal pathogen Candida auris to explore skin tropism, host risk factors and therapeutic strategies.

doi: 10.1016/j.chom.2020.12.002

Figure Lengend Snippet: Figure 4. Skin antiseptic chlorhexidine pro- tects WT mice from C. auris colonization and promotes C. auris decolonization of Rag2–/–Il2rg–/– mice (A) Schematic for experimental design to model CHG skin bathing. Wipes impregnated with CHG were used daily for 4 days to ‘‘bathe’’ the mouse skin before topical association. A cotton gauze saturated with sterile PBS was used as the proce- dural control. C. auris cells were topically associ- ated onto mouse ear pinna and dorsal back skin at two concentrations: 107 CFU as medium concen- tration, and 109 CFU as high concentration. After topical association, CHG was applied every other day for the duration of the experiment. Skin swabs were taken during the experiment and skin tissues were disaggregated at the end of the experiment and processed for C. auris culturing. (B) CHG bathing protects WT mouse skin from C. auris topical exposure (medium and high con- centrations) as measured by culturing skin swabs. n = 4 mice for each group, representative of two independent experiments. (C) CHG bathing protects WT mouse skin tissue from C. auris residence after topical exposure (me- dium and high concentrations). n = 4 mice for each group, representative of two independent experi- ments. (D) Schematic for experimental design to model CHG skin bathing to promote C. auris decoloniza- tion. After C. auris (medium and high concentra- tions) topical association, daily bathing with CHG was deployed for 1 week. Skin swabs were taken during the experiment and skin tissues were dis- aggregated at the end of the experiment for culturing. (E) CHG bathing promotes C. auris decolonization on Rag2/Il2rg/ ear skin swabs 4 and 10 days after high concentration topical exposure. The sta- tistics were calculated using the t test. n = 5 mice for each group, representative of two independent experiments. (F) CHG bathing promotes C. auris decolonization in Rag2/Il2rg/ resident skin tissue after medium and high concentration topical exposure. n = 5 mice for each group, representative of two independent experiments. See also Table S3. The statistics for (B), (C), (E), and (F) were calculated using the t test. *p < 0.05, **p < 0.01.

Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER Yeast Extract-Peptone-Dextrose (YPD) Broth BD Bioscience Cat # 242820 eBioscience Fixation/Permeabilization Concentrate eBioscience Cat #00-5123-43 eBioscience Fixation/Permeabilization Diluent eBioscience Cat #00-5223-56 eBioscience Permeabilization Buffer (10X) eBioscience Cat #00-8333-56 Experimental Models: Organisms/Strains Diabetic mice (db/db) NIAID Taconic Contract N/A Rag2-/-Il2rg-/- NIAID Taconic Contract Line 111 Rag2-/- NIAID Taconic Contract Line 103 Il22-/- Dr. Yasmine Belkaid N/A Card9-/- Dr. Michail S. Lionakis N/A Act1-/- NIAID Taconic Contract Line 290 Lan-DTA Dr. Yasmine Belkaid N/A C57BL/6 mice Taconic Biosciences Cat # B6-F/B6-M C57BL/10 mice NIAID Taconic Contract Line 8411 Oligonucleotides CauF 5’-CGCACATTGCGCCTTGGGGTA-3’ Thermo Scientific N/A CauR 5’-GTAGTCCTACCTGATTTGAGGCGAC-3’ Thermo Scientific N/A Software and Algorithms FlowJo v9 Tree Star https://www.flowjo.com/solutions/ flowjo/downloads GraphPad Prism 4 GraphPad Software https://www.graphpad.com/ scientificsoftware/prism/ R v3.6.0 The R Foundation https://www.r-project.org/ Other Medimachine BD Bioscience Cat # 340588 MediMachine II Syntec International Cat # 121600 LSRFortessa BD Biosciences https://www.bd.com/en-us/offerings/ brands/lsrfortessa LSR II BD Biosciences https://www.bdbiosciences.com/ en-us/go-campaign/lsr-ii-comp-cont QuantStudio 6 Flex Fisher Scientific https://www.fishersci.com/shop/products/ 6-flx96wfast-instlptp-1-system/4485699 GMS staining of mouse ear skin sections Histoserv N/A

Techniques: Sterility, Control, Concentration Assay